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林成源

基本情况

姓  名: 林成源

职  称: 讲师

学  历: 博士研究生

学  位: 博士 

电子邮箱:lincy.hkbu@gmail.com

    林成源,男,汉族,研究助理员,博士。 1979年10月生。2001年毕业于青岛农业大学动物科学系,获学士学位,2004年毕业于青岛农业大学动物科 学院,获得硕士学位,2009年毕业于香港大学生物科学学院,获博士学位;2011年至2015年就职于香港浸会大学中医药学院。2016年3月入职云南 民族大学-香港浸会大学传统天然药物研发联合实验室,从事化学生物学方面的研究,以第一作者、共同通讯作者发表论文15篇。

主要发表的学术论文

1. Lin CY, Jiang X, Hu GF, Ko WK, Wong AO. Grass Carp Prolactin:  Molecular Cloning, Tissue Expression, Intrapituitary Autoregulation by Prolactin and Paracrine Regulation by Growth Hormone and Luteinizing Hormone. Molecular and Cellular Endocrinology,2015, 399:267-283. (IF =3.859),医学2区

2.Hu DD, Han QB, Zhong LL, Li YH, Lin CY, Ho HM, Zhang M, Lin SH, Zhao L, Huang T, Mi H, Tan HS, Xu HX, Bian ZX. Simultaneous determination of ten compounds in rat plasma by UPLC-MS/MS: Application in the pharmacokinetic study of Ma-Zi-Ren-Wan. J Chromatogr B Analyt Technol Biomed Life Sci,2015,1000:136-146. (IF =2.687),医学3区

3.Chen JC, Liu SS, Zhou YY, Li SF, Lin CY, Bian ZX, Fan BM. Palladium/Silver-Cocatalyzed Tandem Reactions of Oxabenzonorbornadienes with Substituted Arylacetylenes: A Simple Method for the Preparation of 1,2-Diarylethanones and 1,2-Diarylacetylenes. Organometallics, 2015, 4318–4322.  (IF =4.186),化学2区

4.Ho SL, Poon CY, Lin CY, Yan T, Kwong DW, Yung KK, Wong MS, Bian Z, Li HW.Inhibition of β-Amyloid Aggregation by Albiflorin, Aloeemodin and Neohesperidin and their Neuroprotective Effect on Primary Hippocampal Cells Against β-Amyloid Induced Toxicity. Curr Alzheimer Res,2015,12(5):424-433. (IF =3.889),医学2区

5.Lin CY, Jiang X, Hu GF, Ko WK, Wong AO. Grass Carp Prolactin:  Molecular Cloning, Tissue Expression, Intrapituitary Autoregulation by Prolactin and Paracrine Regulation by Growth Hormone and Luteinizing Hormone. Molecular and Cellular Endocrinology2015 ,5,399:267-283.(IF 3.859), 医学2区

6. Ho SL, Poon CY, Lin CY, Yan T, Kwong DW, Yung KK, Wong MS, Bian Z, Li HW.Inhibition of β-Amyloid Aggregation by Albiflorin, Aloeemodin and Neohesperidin and their Neuroprotective Effect on Primary Hippocampal Cells Against β-Amyloid Induced Toxicity. Curr Alzheimer Res. 2015,12(5):424-433.(IF 3.889), 医学2区

7.Xiao HT, Qi XL, Liang Y, Lin CY, Wang X, Guan ZZ, Hao XY. Membrane permeability-guided  identification of neuroprotective components from Polygonum cuspidatun. Pharm Biol. 2014, 52(3):356-361.(IF 1.549), 药学 4区

8.Hu J, Yang Q, Xu J, Huang C, Fan B, Wang J, Lin CY, Bian Z, Chan AS. Iridium-Catalyzed Asymmetric Hydroalkynylation Reactions of Oxabenzonorbornadienes. Org Biomol Chem2013,11(5):814-20.(IF 3.562),化学3区

9.Zhang M, Zang KH, Luo JL, Leung FP, Huang Y, Lin CY, Yang ZJ, Lu AP, Tang XD, Xu HX, Sung JJ, Bian ZX. Magnolol inhibits colonic motility through down-regulation of voltage-sensitive L-type Ca2+ channels of colonic smooth muscle cells in rats. Phytomedicine2013,15,20(14):1272-1279.(IF 2.937), 全科医学与补充医学2区

10.Xiao HT, Lin CY, Ho DH, Peng J, Chen Y, Tsang SW, Wong M, Zhang XJ, Zhang M, Bian ZX. Inhibitory effect of the gallotanni.n corilagin on dextran sulfate sodium-induced murine ulcerative colitis. J Nat Prod2013,22,76(11):2120-2125.(IF 3.662), 药物化学2区

 

申请和授权部分专利

1. Zhaoxiang BIAN, Chengyuan LIN, Baomin FAN, Huaixue MU, Yongyun ZHOU, Weimin ZENG, Aiping LU, Sun Chi Albert CHAN. Oxanorbornadiene Derivatives and Their Anticancer Activities. Granted US Patent. US20140187626 A1

2.Chan Albert Sun Chi, Fan Baomin, Lin Chengyuan, Huang Chao, Wang Jun, Hu Jun, Yang Qingqing, Xu Jianbin, Lu Aiping, Bian Zhaoxiang. Asymmetric Synthesis of Norcantharidin Analogues by Alkynylation of Oxabenzonorbornadienes and Their Anticancer Activities. Granted US Patent. US8835658 B2

3.Zhaoxiang BIAN, Chengyuan LIN, Huaixue MU, Baomin FAN, Yongyun ZHOU, Jingchao CHEN, Aiping LU, Sun chi Albert CHAN. Palladium/Silver Co-Catalyzed Tandem Reactions Synthesis of Phenylacetophenone Derivatives by Oxabenzonorbornadienes with Terminal Alkynes and Their Anti-Tumor or Anti-Cancer Activities. US Patent. 2015.06.08, Application No. 14/743,209

4.Zhaoxiang BIAN, Huaixue MU, Chengyuan LIN, Jinjin WANG, Zhijun YANG, Aiping LU, Sun Chi Albert CHAN. Bioactivity Evaluation of Crude Extraction from Lasia spinosa (L.) Thwait and Its main Compounds. US Patent. 2015.06.22, Application No. 62/183,729

5.Zhaoxiang BIAN, Huaixue MU, Chengyuan LIN, Hongxi XU, Dajian YANG, Shilin CHEN, Aiping LU, Sun Chi Albert CHAN. The Study on Bioactivity Evaluation of Crude Extraction from Lasiaspinosa (L.) Thwait and Its main Compounds. US Patent. 2015.06.23, Application No. 62/183,728

6.Zhaoxiang BIAN, Huaixue MU, Chengyuan LIN, Hongxi XU, Dajian YANG, Shilin CHEN, Aiping LU, Sun Chi Albert CHAN. Lignans Isolated from Lasiaspinosa (L.) Thwait Suppressed Metastatic Oesophageal Carcinoma Cell Migration and Invasion in Vitro. 2015.06.23, US Patent. Application No. 62/183,726

7.Zhao-Xiang Bian, Huai-Xue Mu, Cheng-Yuan Lin, Quan-Bin Han, Aiping Lu,Lin-Fang Huang, Shilin Chen, Da-Jian Yang, Hongxi Xu, Albert Sun-Chi CHAN. Coumarins Isolated from Bupleurum malconense for Treating Inflammation. 2014.06.18, US Patent. Application No.  62/013,056

8.Xu Hongxi, Zhang Hong, Lao Yuanzhi, Zhang Dandan, Chen Kaixian, Yang Dajian, Chen Shilin, Lu Aiping, Chan Albert Sun Chi, Bian Zhaoxiang, Lin Chengyuan. Novel Polyprenylated Benzoylphloroglucinols with Anticancer Activity. 2014.01, US Patent. Application No. 14/151,791

9.Xu Hongxi, Zhang Dandan, Zhang Hong, Chen Kaixian, Lin Chengyuan, Yang Dajian, Chen Shilin, Bian zhaoxiang, Lu Aiping, Chan Albert Sun Chi. The usage of Treating Inflammation and Cancer for Natural Compound Garcimultiflorone E from Garcinia esculenta Y.H.Li. 2014.01, US Patent. Application No. 14/149,820

10.Xu Hongxi, Shen Yunhui, Lao Yuanzhi, Cheng Kaixian, Lin Chengyuan, Yang Dajian, Chen Shilin, Bian Zhaoxiang, Lu Aiping, Chan Albert Sun Chi. The use of Sodium Houttuyfonate on Inhibiting Idiopathic Pulmonary Fibrosis and Bleomycin Induced Pulmonary Fibrosis. 2014.01, US Patent. Application No. 14/149,823

11.Xu Hongxi, Zhang Dandan, Zhang Hong, Chen Kaixian, Yang Dajian, Chen Shilin, Bian Zhaoxiang, Lin Chengyuan, Lu Aiping, Chan Albert Sun Chi. The Usage of 1,3,5,7-tetrahydroxy-8-isoprenylxanthone, a Natural Compound from Garcinia esculenta Y.H.Li as Anti-inflammation Drug. 2014.01, US Patent. Application No. US 14/150,726

12.XU Hongxi, ZHANG Hong, LAO Yuanzhi, WANG Xiaoyu, CHEN Kaixian, YANG Dajian, CHEN Shilin, LIN Chengyuan, BIAN Zhaoxiang, LU Aiping, CHAN Albert Sun Chi. A Natural Compound for treating cervical cancer, US Patent. Application No. 61/861,497

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